A single dose of AstraZeneca and one dose of Pfizer / Biontech Coronary Artery Vaccine cause no new side effects, according to a study from Oxford University.
The study showed that bothersome but transient side effects are common after the second dose for those receiving combination vaccines of AstraZeneca and Biontech / Pfizer. These are the known side effects that we reported before, but they are more common in this group, says Chief Physician Sarah Vixmuen Whatley at: National Institute of Health.
Since AstraZeneca is removed from the Norwegian Coronary Artery Grafting Program, many people will have to receive a different vaccine as a second dose.
According to the study of 463 people, those who received two different vaccines were more likely to have headache, chills, fatigue, and other minor side effects than those who received two doses of the same dose, but were no more serious or earlier. unknown. Side effects.
Researchers will now look at how well the combination of two vaccines can protect.
Multiple and mild side effects
Another study, launched in February, found that there were several side effects of mixing vaccines.
The Com-Voc study was launched in the UK in February and examined the side effects of a group receiving the first dose of AstraZeneca vaccine followed by a dose of the Pfizer / Biontech vaccine, a group that received the first dose of the Pfizer / Biontech vaccine and finally one dose of the AstraZeneca vaccine.
In both cases, the doses were set at four-week intervals, and in both cases, participants reported more mild and moderate side effects than those who received the two doses from the same vaccine manufacturer, according to the PA News Agency.
Side effects included symptoms such as cold, fatigue, headache, and fever, and were short-lived, according to preliminary data from the study published in The Lancet.
The researchers note that there are no safety concerns with the mixing of doses.
This part of the study only looked at how patients felt after vaccinations. How immunity is affected has not been considered with the use of doses from different manufacturers.